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2. Scurge Hive (146)
3. Scurge: Hive (139)
4. Seiken Densetsu (53)
5. Shin Megami Tensei DS (48)
6. Shrek SuperSlam (142)
7. SimCity DS (103)
8. Sims 2, The (863)
9. Slime MoriMori: Dragon Quest 2 (46)
10. SNK vs. Capcom Card Fighters Clash (142)
11. SNK vs. Capcom Card Fighters DS (135)
12. Snood 2: On Vacation (33)
13. Snowboard Kids DS (155)
14. Snowboards Kids DS (38)
15. Sonic Rush (173)
16. Sonic Rush Adventure (287)
17. Space Invaders Revolution (126)
18. spectrobes (868)
19. Spelling Challenges And More! (107)
20. Spider-Man: Friend or Foe (1469)
21. Splinter Cell: Chaos Theory (623)
22. Spongebob Squarepants Creature from the Krusty Krab (1345)
23. SpongeBob SquarePants: Lights, Camera, Pants! (40)
24. SpongeBob Squarepants: The Yellow Avenger (82)
25. Sprung (125)
26. Spyro Shadow Legacy (175)
27. Spyro: Shadow Legacy (184)
28. Star Fox Command (439)
29. Star Trek: Tactical Assault (454)
30. Star Wars: Episode 3 - Revenge Of The Sith (378)
31. Star Wars: Revenge of the Sith (76)
32. Star Wars: The Force Unleashed (96)
33. Strawberry Shortcake: Strawberryland Games (65)
34. Sudoku Gridmaster (212)
35. Summon Night Twin Age: Seireitachi no Kyoumei (120)
36. Super Black Bass Fishing (49)
37. Super Mario 64 DS (411)
38. Super Mario Bros. DS (116)
39. Super Monkey Ball Touch and Roll (152)
40. Super Pac-Man Pinball (42)
41. Super Princess Peach (136)
42. Super Robot Taisen W (572)
43. Super Robot Wars DS (35)
44. Superman Returns: The Videogame (628)